Correction: Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
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Copyright: © 2015 Tengvall et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
منابع مشابه
Genome-Wide Analysis in German Shepherd Dogs Reveals Association of a Locus on CFA 27 with Atopic Dermatitis
Humans and dogs are both affected by the allergic skin disease atopic dermatitis (AD), caused by an interaction between genetic and environmental factors. The German shepherd dog (GSD) is a high-risk breed for canine AD (CAD). In this study, we used a Swedish cohort of GSDs as a model for human AD. Serum IgA levels are known to be lower in GSDs compared to other breeds. We detected significantl...
متن کاملComparison of cellular location and expression of Plakophilin‐2 in epidermal cells from nonlesional atopic skin and healthy skin in German shepherd dogs
BACKGROUND Canine atopic dermatitis (CAD) is an inflammatory and pruritic allergic skin disease caused by interactions between genetic and environmental factors. Previously, a genome-wide significant risk locus on canine chromosome 27 for CAD was identified in German shepherd dogs (GSDs) and Plakophilin-2 (PKP2) was defined as the top candidate gene. PKP2 constitutes a crucial component of desm...
متن کاملGenetic Studies in Dogs Implicate Novel Genes Involved in Atopic Dermatitis and IgA Deficiency
Tengvall, K. 2015. Genetic Studies in Dogs Implicate Novel Genes Involved in Atopic Dermatitis and IgA Deficiency. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1128. 88 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9304-2. This thesis presents genetic studies of atopic dermatitis (AD) and IgA deficiency in dogs. AD is a chronic inflammator...
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Selective IgA deficiency (IgAD) is the most common primary immunodeficiency disorder in Caucasians and is defined as serum IgA concentrations below or equal to 0.07 g/l, with normal serum concentrations of IgM and IgG, in individuals 4 years of age or older. The prevalence of IgAD is approximately 1:600 in the general population and recent results have shown that patients with IgAD have signifi...
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Concurrent disorders with diabetes mellitus is one of the most challenging subject. Our knowledge of the most common concurrent disorders in diabetic dogs may be useful in diagnosis of these disorders and better treatment of diabetic dogs. In this study diabetes mellitus was diagnosed in a 7-year-old male German shepherd dog, based on clinical and laboratory findings. Following the diagnosis of...
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عنوان ژورنال:
دوره 11 شماره
صفحات -
تاریخ انتشار 2013